Launchy
Just hit "Alt+Enter" and fireup your app. Recognizes all installed apps and adapts itself.
Tomboy Notes
Use a shortcut like "Shift<F1>" and you paste your notes with a heading. Press Esc and forget about it(automatically saved). You can get it along with all the other notes with another shortcut key.
GTD Timer
The best timer/reminder app I have seen till date. Trial version.. 
Inspired to write my own app based on this. Design already done!
Windows Live Writer
Again the best for maintaining multiple blogs! Surprising to see such a product from MS. I think most of us have it installed with as part of "Windows Live"
Google Chrome
Those willing to try it..can go ahead..very excellent interface..except "on the fly bookmarks" Badly missing this feature.
StickyPad
This piece of software from greeneclipse software is a real gem. The UI is good and has a very high usability index.
